Chemical and Biomolecular Engineering

Mayuresh V. Kothare

Associate Dean for Research and R. L. McCann Professor

(610) 758 6654

mvk2@lehigh.edu

Whitaker Lab 546 and Packard Lab 308, 5 East Packer Avenue, Bethlehem, PA 18015

Faculty Webpage

Google Scholar

ORCID 0000-0001-7681-7445

169

Publications

11,654+

Citations

h-index

Active Grants

Biography

Mayuresh V. Kothare is the R. L. McCann Professor of Chemical and Biomolecular Engineering at Lehigh University, where he has been a faculty member since 1998. Since 2024, he has also served as Associate Dean for Research in the P. C. Rossin College of Engineering and Applied Science. His research spans robust model predictive control, microchemical systems, and biomedical applications, with additional affiliations in Lehigh's Departments of Bioengineering and Electrical Engineering.

Kothare's work has had meaningful real-world impact, including the development of medical oxygen concentrator technology that led to the founding of two spin-off companies—Pharmateck LLC and Omnilife Systems Private Ltd.—aimed at delivering personalized oxygen therapy to underserved and remote populations. His scholarly contributions are widely recognized, with an h-index of 40 and more than 11,600 citations to his credit, reflecting the sustained influence of his research across control systems engineering and beyond.

Areas of Research

Model predictive control
Robust constrained control
Linear matrix inequalities
Anti-windup control
Microchemical systems
Pressure swing adsorption
Medical oxygen concentrators
Closed-loop neuromodulation
Brain-machine interfaces
Vagus nerve stimulation
Cardiovascular system modeling and control
Data-driven dynamical systems modeling
Embedded control systems
Gastrointestinal system modeling
Gene regulatory network modeling

Appointments & Honors

Current Appointments

2024–Associate Dean for Research, Rossin College of Engineering & Applied Science, Lehigh University (2024 - present)
2022–Affiliated Faculty Member, College of Health, Lehigh University (2022 - present)
2018–Professor of Electrical Engineering (by courtesy), Lehigh University (2018 - present)
2017–Affiliated Faculty Member, Dept. of Bioengineering, Lehigh University (2017 - present)
2008–Professor of Chemical Engineering and R. L. McCann Professor, Lehigh University (June 2008 - present)
2004–R. L. McCann Professor, Lehigh University (July 2004 - present)

Selected Honors

2026Elected Senior Member, National Academy of Inventors (NAI)
2024Elected Fellow, American Association for the Advancement of Science (AAAS)
2023High Impact Paper Award, International Federation of Automatic Control (IFAC)
2020Distinguished Alumnus Award, Indian Institute of Technology, Bombay
2018Elected Fellow, American Institute of Chemical Engineers (AIChE)
2017Inaugural Speaker, Distinguished Lecture Series in Control Science & Engineering, Zhejiang University

Teaching

CHE233/234Process/Plant Design
CHE185/186Undergraduate Research
CHE202/203Unit Operations Laboratory
CHE242Introduction to Process Control and Simulation
CHE434Multivariable Process Control

BIO142/BIO242Bioengineering Research
CHE201Methods of Analysis in Chemical Engineering
CHE280Unit Operations Survey
BIOE/CHE339/439Neuronal Modeling and Computation
CHE395/495Applied Data Science

Full Record

Research Assistant, IIT Bombay (June-July 1991)
Research Assistant, California Institute of Technology (September 1991 - September 1994)
Research Assistant, Swiss Federal Institute of Technology (ETH), Zürich (September 1994 - December 1996)
Visiting Scholar, Dept. of Electrical Engineering, Purdue University (June-July 1996)
Visiting Scholar, Dept. of Chemical Engineering, City College of New York (January-June 1997)
Postdoctoral Research Associate, Mobil Technology Company, NJ (July 1997 - June 1998)
Assistant Professor, Dept. of Chemical Engineering, Lehigh University (July 1998 - June 2003)
Faculty Member, Chemical Process Modeling & Control Center, Lehigh University (July 1998 - 2012)
P. C. Rossin Assistant Professor of Chemical Engineering, Lehigh University (July 2001 - June 2003)
Co-Director, Chemical Process Modeling and Control Research Center, Lehigh University (2002 - 2012)
Frank Hook Assistant Professor of Chemical Engineering, Lehigh University (September 2002 - August 2004)
Associate Professor of Chemical Engineering, Lehigh University (July 2003 - June 2008)
Class of 1961 Associate Professor, Lehigh University (April - June 2004)
R. L. McCann Professor, Lehigh University (July 2004 - present)
Professor of Chemical Engineering and R. L. McCann Professor, Lehigh University (June 2008 - present)
Visiting Professor, Johns Hopkins School of Medicine, Baltimore, MD (September 2008 - August 2012)
Visiting Professor, East China University of Science and Technology, Shanghai (June 2012)
Chair, Dept. of Chemical & Biomolecular Engineering, Lehigh University (July 2012 - June 2021)
Distinguished Guest Professor, East China University of Science and Technology, Shanghai (August 2012 - July 2015)
Affiliated Faculty Member, Dept. of Bioengineering, Lehigh University (2017 - present)
Professor of Electrical Engineering (by courtesy), Lehigh University (2018 - present)
Affiliated Faculty Member, College of Health, Lehigh University (2022 - present)
Associate Dean for Research, Rossin College of Engineering & Applied Science, Lehigh University (2024 - present)

1984 — Ranked in first fifty students of Bombay in the Bombay Talent Search examination
1986 — Selected as state level representative to Indian National Mathematics Olympiad
1991 — Silver Medal for ranking first in graduating class, Dept. of Chemical Engineering, IIT Bombay
1991 — Reliance Heat Transfer Pvt. Ltd. prize for most outstanding student graduating from Chemical Engineering, IIT Bombay
1991 — J. N. Tata Endowment prize for outstanding students pursuing graduate studies outside India
1991 — Sumant Mulgaonkar Memorial Award, Jamsetji Tata Trust, India, for academic excellence
1991 — Union Oil Graduate Fellowship, California Institute of Technology
2000 — Ted Peterson Student Paper Award, Computing & Systems Technology (CAST) Division of AIChE
2001 — Junior faculty (starter) grant, Petroleum Research Fund of the American Chemical Society
2001 — P. C. Rossin Assistant Professorship, Rossin Endowment, P. C. Rossin College of Engineering & Applied Sciences, Lehigh University
2001 — Outstanding Reviewer for Automatica, IFAC
2002 — Faculty Early Career Development (CAREER) Award, National Science Foundation
2002 — Alfred Noble Robinson Award, Lehigh University
2002 — Frank Hook Assistant Professorship, Lehigh University
2003 — Best Presentation in Session, American Control Conference, Denver, CO
2004 — Class of 1961 Associate Professorship, Lehigh University
2004 — R. L. McCann Professorship, Lehigh University
2007 — Outstanding Young Researcher Award (under 40 years), CAST Division of AIChE
2008 — Selected to National Academy of Engineering's 14th Annual U.S. Frontiers of Engineering Workshop
2012 — Elected Fellow, Institute of Electronics and Electrical Engineers (IEEE)
2012 — Guest Professorship, East China University of Science and Technology, Shanghai
2016 — Listed in Most-cited Researchers in Electrical & Electronics Engineering, Shanghai Global Ranking
2017 — Inaugural Speaker, Distinguished Lecture Series in Control Science & Engineering, Zhejiang University
2018 — Elected Fellow, American Institute of Chemical Engineers (AIChE)
2020 — Distinguished Alumnus Award, Indian Institute of Technology, Bombay
2023 — High Impact Paper Award, International Federation of Automatic Control (IFAC)
2024 — Elected Fellow, American Association for the Advancement of Science (AAAS)
2026 — Elected Senior Member, National Academy of Inventors (NAI)

Perspectives in Constrained Process Control: Theory and Practice, Industrial Advisory Committee Meeting, Chemical Process Modeling & Control Center, Lehigh University, 1997
A Framework for Scheduled Output Feedback Model Predictive Control for Constrained Nonlinear Systems, 7th IFAC Symposium on Advanced Control of Chemical Processes (ADCHEM), Hong Kong, 2004
Synthesis of Controllers for Constrained Systems, 24th Annual Benelux national meeting on Systems and Control, Houffalize, Belgium, 2005
Dynamics and Control of Integrated Microchemical Systems, 24th Annual Benelux national meeting on Systems and Control, Houffalize, Belgium, 2005
Dynamics and Control of Integrated Microchemical Systems, 7th Conference on Chemical Process Control (CPC7), Lake Louise, Alberta, Canada, 2006
Linear Matrix Inequalities in Chemical Process Control, 2007 Advanced Process Control workshop, Vancouver, BC, Canada, 2007
Broadcast Model Predictive Control of Multi-Cellular Systems, AIChE CAST Division Plenary Session, 2009
Dynamics and Control of Integrated Microchemical Systems, 10th IFAC Symposium on Advanced Control of Chemical Processes (ADCHEM), Singapore, 2012
Non-Equilibrium, Non-Isobaric, Non-Isothermal Desorption of Nitrogen from a LiX Zeolite Column, 11th International Conference on the Fundamentals of Adsorption, Baltimore, MD, 2013
Multi-Model Predictive Control: Controller Formulation and Application to Medical Oxygen Concentrators, Distinguished Lecture Series in Control Science & Engineering, Zhejiang University, 2017
Multi-Model Predictive Control: Controller Formulation and Application to Medical Oxygen Concentrators, Azeotropy 2019, IIT Bombay, 2019
A Unified Framework for the Study of Anti-Windup Control Systems, California Institute of Technology, 1993
Robust Constrained Model Predictive Control using Linear Matrix Inequalities, Swiss Federal Institute of Technology (ETH), Zürich, 1995
Constrained Control of Linear Systems, Swiss Federal Institute of Technology (ETH), Zürich, 1996
Control of Constrained Systems, City College of New York, 1997
Control of Systems Subject to Constraints, Lehigh University, 1997
Perspectives in Constrained Process Control: Theory and Practice, Lehigh University, 1999
Constrained Process Control: Theory and Practice, Dept. of Mechanical Engineering, Lehigh University, 2000
Some Research Problems in Constrained Process Control and Integrated Microchemical Systems, Chemical Process Modeling and Control Research Center, Lehigh University, 2000
An Integrated Chemical Reforming Microplant for Fuel Cell Applications, NSF grantees workshop, Washington DC, 2000
Chemical Microplant on a Chip: Miniature Fuel Processing for Portable Power, Pittsburgh Digital Greenhouse, 2000
Some Research Problems in Constrained Process Control and Integrated Microchemical Systems, University of Delaware, 2001
Smart Microchemical Plant-on-Chip for High Performance Microscale Portable Power, Pittsburgh Digital Greenhouse, 2001
Research in Linear Matrix Inequalities and Integrated Microchemical Systems, ExxonMobil Chemical Company, Baytown, Texas, 2001
Integrated Microchemical Systems: Chemical Plant-on-chip, Lehigh University, 2001
Smart Microchemical Plant-on-Chip for High Performance Microscale Portable Power, Pittsburgh Digital Greenhouse, 2002
Issues in Micro and Nano-scale Power Devices, Pennsylvania Nanotechnology 2002, Harrisburg, PA, 2002
Linear Matrix Inequalities in Systems and Control, Industrial and Systems Engineering, Lehigh University, 2002
Analysis and Synthesis of Feedback Controllers for Actuator Limited Multivariable Systems, Dept. of Mathematics, Lehigh University, 2003
Fuel Processing Microreactors for Hydrogen Production by Methanol Reforming, Knowledge Foundation's 5th International Symposium Small Fuel Cells 2003, New Orleans, LA, 2003
Integrated Microchemical Systems with Applications in Micro-Reforming, Corning Incorporated, 2003
Integrated Microchemical Systems with Applications in Micro-Reforming, City College of the City University of New York, 2003
Integrated Microchemical Systems, New Jersey Center for Microchemical Systems, Stevens Institute of Technology, 2004
A Framework for Design of Scheduled Model Predictive Control for Constrained Nonlinear Systems, DuPont, Wilmington, DE, 2004
High Performance Embedded Model Predictive Control System-on-Chip, Pittsburgh Digital Greenhouse, 2004
Control and Dynamical Systems Research at Lehigh University, Petrobras, Rio de Janeiro, Brazil, 2005
Efficient Scheduled Stabilizing Model Predictive Control for Constrained Nonlinear Systems, International Workshop on Assessment and Future Directions of Nonlinear Model Predictive Control, Germany, 2005
Integrated Microchemical Systems with Application to Micro-Scale Fuel Processing, Ecole Polytechnique Montreal, Canada, 2005
Integrated Microchemical Systems with Application to Micro-Scale Fuel Processing, University of Pittsburgh, 2005
Synthesis of Controllers for Constrained Systems, University of Washington, Seattle, 2005
Synthesis of Controllers for Constrained Systems, University of Alberta, Edmonton, Canada, 2006
Efficient Scheduled Model Predictive Control for Constrained Nonlinear Systems, NSF workshop on Mathematical Modeling and Control of Plasmas in Magnetic Fusion, 2006
Dynamics and Control of Integrated Microchemical Systems, University of California Santa Barbara, 2006
Dynamics and Control of Integrated Microchemical Systems, GE Water and Process Technology, Trevose, PA, 2007
Synthesis of Controllers for Constrained Systems, East China University of Science & Technology, Shanghai, 2012
Control of Constrained Multivariable Systems using Linear Matrix Inequalities, Zhejiang University, China, 2012
Modeling and Control Problems in Closed-Loop Neuroprosthetic Systems, LFHM Seminar Series, Philadelphia, PA, 2013
Overview of Research in Dynamics and Control of Chemical and Neural Systems, Universiti Teknologi Petronas, Malaysia, 2013
Multi-Model Predictive Controller Formulation and Application to Medical Oxygen Concentrators, East China University of Science & Technology, Shanghai, 2017
Multi-Model Predictive Controller Formulation and Application to Medical Oxygen Concentrators, Zhejiang University, China, 2017
Multi-Model Predictive Control: Controller Formulation and Application to Medical Oxygen Concentrators, Columbia University, 2018
Multi-Model Predictive Control: Controller Formulation and Application to Medical Oxygen Concentrators, San Jose State University, 2021
In-silico Modeling and Control of Cardiovascular Dynamics, University of South Florida, Tampa, FL, 2025